Metabolic Response of Clostridium ljungdahlii to Oxygen Exposure
نویسندگان
چکیده
منابع مشابه
Lactose-inducible system for metabolic engineering of Clostridium ljungdahlii.
The development of tools for genetic manipulation of Clostridium ljungdahlii has increased its attractiveness as a chassis for autotrophic production of organic commodities and biofuels from syngas and microbial electrosynthesis and established it as a model organism for the study of the basic physiology of acetogenesis. In an attempt to expand the genetic toolbox for C. ljungdahlii, the possib...
متن کاملCharacterizing acetogenic metabolism using a genome-scale metabolic reconstruction of Clostridium ljungdahlii
BACKGROUND The metabolic capabilities of acetogens to ferment a wide range of sugars, to grow autotrophically on H2/CO2, and more importantly on synthesis gas (H2/CO/CO2) make them very attractive candidates as production hosts for biofuels and biocommodities. Acetogenic metabolism is considered one of the earliest modes of bacterial metabolism. A thorough understanding of various factors gover...
متن کاملExpanding the molecular toolkit for the homoacetogen Clostridium ljungdahlii
Increasing interest in homoacetogenic bacteria for the production of biochemicals and biofuels requisites the development of new genetic tools for these atypical production organisms. An attractive host for the conversion of synthesis gas or electricity into multi-carbon compounds is Clostridium ljungdahlii. So far only limited achievements in modifying this organism towards the production of i...
متن کاملGlobal metabolic response of Enterococcus faecalis to oxygen.
Oxygen and oxidative stress have become relevant components in clarifying the mechanism that weakens bacterial cells in parallel to the mode of action of bactericidal antibiotics. Given the importance of oxidative stress in the overall defense mechanism of bacteria and their apparent role in the antimicrobial mode of action, it is important to understand how bacteria respond to this stress at a...
متن کاملEffect of Organic Substrate on Promoting Solventogenesis in Ethanologenic Acetogene Clostridium ljungdahlii ATCC5538
Clostridium ljungdahlii is a strictly anaerobic acetogene known for its ability to ferment a wide variety of substrates to ethanol and acetate. This bacterium presents a complex anaerobic metabolism including the acetogenic and solventogenic phases. In this study, the effect of various carbon sources on triggering the metabolic shift toward solventogenesis was considered. The bacterium was grow...
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ژورنال
عنوان ژورنال: Applied and Environmental Microbiology
سال: 2015
ISSN: 0099-2240,1098-5336
DOI: 10.1128/aem.02491-15